Respiration & Nasal Vaccination
Respiration model, nasal cavity, trachea, lungs, and pulmonary circulation can be simulated using full 3D model, distributed 1D tree model, or compartmental models. The respiration model includes air and particulates in/out flow in nasal/throat cavity, trachea/bronchial tree, up to the alveoli, alveolar air-blood barrier, and gas exchange between air and pulmonary blood. It is coupled to whole body hemodynamics and metabolism models and can be used to simulate exercise, hypoxia, asthma, inhalation drug or nasal vaccine delivery, viral infection, blunt or pulmonary blast injury.
In collaboration with CDC and Johns Hopkins University, CFDRC has created a database of nasal cavity geometries that can be used for simulations and experiments. The phantom models have flexible noses and/or flexible faces. Various age groups are available, see list of available Phantom models.
